Trusted Prescription Drug Information

• If you experience any of the following serious side effects, stop using Ortho Evra and seek emergency medical attention or contact your doctor immediately:
· an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
· sharp chest pain, coughing blood or sudden shortness of breath (possible blood clot in the lung);
· pain in the calf (possible blood clot in the leg);
· crushing chest pain or heaviness in the chest (possible heart attack);
· sudden severe headache or vomiting, dizziness, faintness or problems with vision or speech, weakness or numbness in an arm or leg (possible stroke);
· sudden partial or complete loss of vision (possible clot in the eye);
· yellowing of the skin or whites of the eyes (jaundice), especially with fever, tiredness, loss of appetite, dark colored urine, or light colored bowel movements (possible liver problems);
· severe pain, swelling, or tenderness in the abdomen (gallbladder or liver problems);
· irregular vaginal bleeding or spotting that happens in more than 1 menstrual cycle or lasts for more than a few days;
· swelling (edema) of the fingers or ankles; or
· severe problems with difficulty sleeping, weakness, lack of energy, fatigue, or a change in mood (possible severe depression).
· new or changing breast lumps.
• Other, less serious side effects may be more likely to occur. Continue to use Ortho Evra and talk to your doctor if you experience
· headache or dizziness;
· changes in menstrual cycle or breast tenderness;
· changes in weight or appetite;
· water retention;
· intolerance to contact lenses;
· changes in skin color; or
· changes in blood sugar.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

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